Superoxide dismutase (SOD) is an antioxidant enzyme used in skincare to combat oxidative stress, reduce premature skin aging, and protect against environmental damage (including UV radiation). It plays a crucial role in protecting cells from oxidative stress by catalyzing the dismutation of superoxide radicals (O2-) into oxygen and hydrogen peroxide. SOD acts as a cellular defense mechanism, protecting cells from damage to DNA, proteins, and lipids.(1-2)

In an in vivo study, superoxide dismutase, combined with glycine soja protein and hydrolyzed rice protein, was shown to improve skin texture; in an in vitro study, it was shown to improve capillary blood flow and stimulate fibroblast proliferation.(3)