Dimethylisosorbide is a solvent that, due to its high penetrating power, is used to enhance the penetration of active ingredients into the skin. This can improve the effectiveness of the various ingredients.(1)
(1) Zhang, Y., Kung, C. P., Iliopoulos, F., Sil, B. C., Hadgraft, J., & Lane, M. E. (2021). Dermal Delivery of Niacinamide—In Vivo Studies. Pharmaceutics, 13(5), 726. https://doi.org/10.3390/pharmaceutics13050726
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