BISABOLOL
Bisabolol is an active ingredient (sesquiterpene) that was originally derived from plants, such as chamomile (Matricaria chamomilla). Chamomile extract therefore naturally contains α-bisabolol. The active ingredient is valued for its anti-inflammatory, skin-soothing, and antimicrobial properties. Bisabolol can help alleviate skin irritation and support the regeneration of irritated skin or skin prone to redness.(1-5)
(1) Maurya, A., Singh, M., Dubey, V., Srivastava, S., Luqman, S., Bawankule, D. (2014). α-(-)-Bisabolol reduces pro-inflammatory cytokine production and alleviates skin inflammation. Current Pharmaceutical Biotechnology, 15(2), 173–81.
(2) Kamatou, G. P. P., Viljoen, A. M. (2010). A review of the application and pharmacological properties of α-bisabolol and α-bisabolol-rich oils. Journal of the American Oil Chemists' Society, 87(1), 1–7.
(3) Li G, Wu H, Sun L, Cheng K, Lv Z, Chen K, Qian F, Li Y. (2022). (-)-α-Bisabolol Alleviates Atopic Dermatitis by Inhibiting MAPK and NF-κB Signaling in Mast Cells. *Molecules*. 27(13), 3985.
(4) Park J, Han F, Lee IS. (2022). Biotransformation of (-)-α-Bisabolol by Absidia coerulea. Molecules. 27(3), 881.
(5) Bährle-Rapp, M. (2012). Springer Encyclopedia of Cosmetics and Personal Care. 4th revised and expanded edition. Springer.
